Pregnancy outcomes in patients exposed to interferon beta-1b

withstand the 20 min rotation, some were not completely immune, perhaps because of residual vestibular function. Some degree of otolith function could still be present since caloric and rotational tests primarily assess horizontal semicircular canal function. It is also known that visual stimuli can provoke symptoms, and since the experiment took place in the light, this may be an alternative explanation. Seasickness commonly has a negative impact on leisure and tourism activities such as sailing and cruise travel. Ability to identify positive aspects of a condition can predict outcome in chronic conditions. We therefore recommend that patients with BVF be advised of this beneficial aspect of their condition. Those with VN, a unilateral lesion, do not share this beneficial effect. There is an overall increase in motion sickness susceptibility of patients with VM but this is not different from migraine. This contrasts with findings of previous studies that have shown higher susceptibility scores in questionnaires in VM than migraine in general. Unlike any previous study, the questionnaire data from our study are supported by the experimental data. Some individuals with VM reported reductions in susceptibility, suggesting some heterogeneity in the underlying pathomechanism, which could also explain some observed differences between ours and previous studies. In conclusion, BVF reduces motion sickness susceptibility, and this can be regarded as a beneficial effect of this disorder, but a unilateral lesion is insufficient to trigger such a reduction. VM and migraine similarly enhance motion sickness susceptibility profiles.